IDENTIFICATION OF A GENOMIC DNA SEQUENCE THAT QUANTITATIVELY MODULATES KLF1 TRANSCRIPTION FACTOR EXPRESSION IN DIFFERENTIATING HUMAN HEMATOPOIETIC CELLS

Identification of a genomic DNA sequence that quantitatively modulates KLF1 transcription factor expression in differentiating human hematopoietic cells

Abstract The onset of erythropoiesis is under strict developmental control, with direct and indirect inputs influencing its derivation from the hematopoietic stem cell.A major regulator of this transition is KLF1/EKLF, a Hooded Tech Tee zinc finger transcription factor that plays a global role in all aspects of erythropoiesis.Here, we have identifi

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